Modeling gene and genome duplications in eukaryotes

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چکیده

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Modeling gene and genome duplications in eukaryotes.

Recent analysis of complete eukaryotic genome sequences has revealed that gene duplication has been rampant. Moreover, next to a continuous mode of gene duplication, in many eukaryotic organisms the complete genome has been duplicated in their evolutionary past. Such large-scale gene duplication events have been associated with important evolutionary transitions or major leaps in development an...

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The importance of gene gain through duplication has long been appreciated. In contrast, the importance of gene loss has only recently attracted attention. Indeed, studies in organisms ranging from plants to worms and humans suggest that duplication of some genes might be better tolerated than that of others. Here we have undertaken a large-scale study to investigate the existence of duplication...

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Introduction – homology and the evolution of protein families Delineation of protein families Ancient gene duplications and the root of the tree of life Gene and genome duplications, speciation, and innovation in eukaryotes Convergence versus concerted evolution

Abbreviations Introduction – homology and the evolution of protein families Delineation of protein families Ancient gene duplications and the root of the tree of life Gene and genome duplications, speciation, and innovation in eukaryotes Convergence versus concerted evolution Conclusions Acknowledgements References and recommended reading Copyright

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2005

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0501102102